I booked the Serrano as part of a trip as a present to my Mother for her 65th birthday.

She was a bit nervous at first as this was her first visit to the USA, but within minutes of arriving she felt right at home.

All the staff we came across were friendly and welcoming, and the service we received from the doormen, check-in staff and restaurant staff was excellent from start to finish.

We stayed in on of the 'Luxury Suites' on the 14th floor. The rooms were big and clean with a 32" flat screen in the bedroom and living room. The 'Honor Bar' was well stocked and the bathroom was a tidy size. The nighty wine reception in the lobby from 5 to 6 was also a great bonus.

Don't let the comments about the location worry you, it's only a couple of minutes walk to Union Square and we never felt threatened around the hotel once.

I would have no problem recommending this hotel to anyone and would definetally stay here again if I was lucky enough to visit San Francisco again.

Thanks once again to Mr Flores and his staff for a great stay.

Great, Great 4 day stay - 40 dollars from airport and never needed a car (rental comapanies are all around corner if you do need car vs. airport - caution - parking is very expensive everywhere in SF)
Hotel has charm and character and is great retreat after long day or night.
Great hotel for work or leisure. Friendly, helpful. Unique.
A great experience.
Would definitely stay again.
Walkable to all conference locations - 2-5 easy and entertaining blocks.
Great and varied food in area from diners, mexican, thai, chinese, you name it.

We've stayed at many hotels in SF, and this is one I look forward to staying at often. World class service from the door man to the ladies working the floors, and unbelievable five star experience with the front desk. If I knew the gentleman's name working the desk early evening of 9/1/8, I would lavish him with praise. He really made our stay a special experience. Highly Recommend this hotel for San Francisco luxury at an affordable price, great location near shopping, dining, cable cars... Excellent opportunity for business travelers, family vacations, and they even accept pets, we saw beautiful little dogs with their happy companions. Beds are float in the clouds comfortable, can't say enough good things about the Serrano, play the check in game and donate to your favorite charity!! Thank you Serrano & Hotwire for showing the way...

We stayed five days at the Serrano making it a long labor day weekend. The hotel was very busy but operations were smooth. It is an excellent place to bring a little child - the crib was brought in no time to the room and we had a high-chair in the room for the entire duration of our stay. The room was very quiet, we were lucky to be on the 15th floor where we almost couldn't hear the traffic down there.
It's true that the standard room we had was on the small side but it was OK for the three of us. The restaurant (Ponzu) where breakfast is served is OK but not so much my style and rather expensive. San Fran has better places if you go out there! Also be aware of the minibar: it's full of goodies but no free lunch!
Location is very convenient with easy access to the city (we walked to Fisherman's on the first day) and public transport on Market Street and the shops. If you take Powell Street to go to Market St you can avoid the Tenderloin area which I'd advise