The population of Chilean Patagonia is made up of various types of immigrants from all over the world, though majority is from Europe originally. For instance, the German influence in Chile can be obvious at times, as in Puerto Montt, it is possible to eat Kuchen, which are German cakes, and savor delectable home-made chocolates. Thus, there are both brown hair and blond haired, blue-eyed locals in Patagonia.

The Chilean portion of Patagonia tends to be quieter than the Argentinean portion and may not be as openly friendly and can be known to keep to themselves. Travelers should be conscientious of being polite and respectful. One sure way to start conversation is to go to a bar during a Chilean futbol (aka soccer) match. Also, Chileans are known for their Parrillada displays (much like Argentines) where they barbeque the stomachs, livers, and flanks of cows. Overall, traveling through the smaller towns of Chilean Patagonia can give a traveler a good sense of what life is really like there, rather than some of the more touristy towns in Argentinean Patagonia, which is more spectacle than reality. Regardless, when traveling in Chile, some parts of Patagonia are not inhabited and it can be days before seeing another traveler.